Eliad Davidson (Pain medicine)
Prof. Davidson is the Director of the pain relief unit in Hadassah Hebrew University Medical Center. He completed his anesthesiology residency in Hadassah Hebrew University Medical Center and earned higher education in pain practice and research in the University of Texas-Houston School of Medicine (2 years Herman hospital) and in the University of Miami School of Medicine (1 year Jackson Memorial). Prof. Davidson was a board member of the Israeli Pain Association and is the current president of IASP. He is involved in educating the medical community and public regarding pain management.
1. Local anesthetics and Liposomal long acting local anesthetics.
2. Genetic Polymorphism of the mu opioid receptor.
3. Effect of Neuroaxial Injections on MR Imaging. Studies comparing spinal MRI prior vs MRI following epidural injections in patients treated for low back pain or after epidural infusions.
4. Use of Medical Cannabis- preclinical and clinical research.
5. Patient Safety
Davidson EM, Sklar EM, Bhatia RG, Garcia L, Hulen R, Ginosar Y, Arheart K and Birnbach DPI. (2008) Evaluation of MR Imaging Following Neuraxial Steroid Injection. A Prospective Study to Determine Whether Epidural Injection Produces Pathologic MRI Findings. Reg Anesth Pain Med 33(4):326-31
Haroutiunian, S , Shoval R, Rosen G, Davidson EM. (2008) Open-label, add-on study of tetrahydrocannabinol for chronic non-malignant pain. J Pain Palliative Care Pharmocother 22(3):213-17.
Ginosar Y, Nadjari M, Hoffman M, Firman N, Davidson EM, Rosen L, Weissman C, and Elchalal U and the ACET study group. (2009).Antepartum continuous epidural ropivacaine therapy reduces uterine artery vascular resistance in preeclampsia: a randomised, dose-ranging, placebo-controlled study. Br J Anesth BJA 102(3): 369-78.
Ginosar Y, Weiniger CF, Kurz V, Babchenko A, Nitzan M and Davidson EM. (2009) Sympathectomy-mediated vasodilatation: a randomized concentration ranging study of epidural bupivacaine. Can J Anesth 56(3): 213-21.
Haroutiunian S, Lecht S, Zur AA, Hoffman A, Davidson EM. (2009) The challenge of pain management in patients with myasthenia gravis. J Pain Palliat Care Pharmacother. 23(3):242-60.
Ginosar Y, Davidson EM, Meroz Y, Blotnick S, Shacham M, Caraco Y. (2009) Mu-opioid receptor (A118G) single-nucleotide polymorphism affects alfentanil requirements for extracorporeal shock wave lithotripsy: a pharmacokinetic-pharmacodynamic study. Br J Anaesth. 103(3):420-7.
Ginosar Y, Weiniger CF, Meroz Y, Kurz V, Bdolah-Abram T, Babchenko A, Nitzan M, Davidson EM. Pulse oximeter perfusion index as an early indicator of sympathectomy after epidural anesthesia. Acta Anaesthesiol Scand. 2009 53(8):1018-26.
Davidson EM, Barenholz Y, Cohen R, Haroutiunian S, Kagan L, Ginosar Y.(2010) High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous administration in humans. Anesth Analg. 110(4):1018-23.
Davidson EM, Sklar E, Bahatia R, Garcia LC, Ginosar Y, Arheart K and Birnbach D. (2010) MRI findings following uneventful continuous infusion neuraxial analgesia. A Prospective Study to Determine Whether Epidural Infusion Produces Pathologic MRI Findings. Anesth Analg 110(1):233-7.
Ginosar YPI, Smith YC, Ben-Hur TC, Lovett JMC, Clements TC, Ginosar YDC, Davidson EPI. (2012) A novel pulsatile CSF model to assess pressure manometry and fluid sampling through spinal needles of different gauge: support for the use of a 22G spinal needle with a tapered 27G pencil-point tip. Br J Anesth BJA 108(2):308-15
Zaslansky RPI, Chapman CRC, Rothaug JC, Backstrom RC, Brill SC, Davidson EC, Elessi KC, Fletcher DC, Fodor LC, Karanja EC, Konrad CC, Kopf AC, Leykin YC, Lipman AC, Puig MC, Rawal NC, Schug SC, Ullrich KC, Volk T, Meissner WPI. (2012) Feasibility of international data collection and feedback on postoperative pain data: Proof of concept. Eur J Pain 16(3):430-8
Ginosar YPI, Birnbach DJC, Shirov TTC, Arheart KC, Caraco YC, Davidson EMPI. (2013) Duration of analgesia and pruritus following intrathecal fentanyl for labour analgesia: no significant effect of A118G ?-opioid receptor polymorphism, but a marked effect of ethnically distinct hospital populations. Br J Anaesth 111(3):433-44
Haroutiunian SPI, Kagan LC, Yifrach-Damari IC, Davidson EC, Ratz YC, Hoffman API. (2014) Enhanced antinociceptive efficacy of epidural compared with i.v. methadone in a rat model of thermal nociception. Br J Anaesth 112:150-8
Davidson EPI, Haroutiunian SC, Kagan LC, Naveh MC, Cooper SC, Aharon AC, Ginosar YPI (2016) Subcutaneous administration of proliposomal 4% ropivacaine in healthy human volunteers: pharmacokinetic and pharmacodynamic data. Anesth Analg
Davidson EPI, Haroutiunian SC, Kagan LC, Naveh MC, Cooper SC, Aharon AC, Ginosar YPI. (2016) Subcutaneous administration of proliposomal ropivacaine: preclinical studies of toxicity, pharmacodynamics, pharmacokinetics, and wound healing. Anesth Analg
Haroutiunian SPI, Ratz YC, Ginosar YC, Karina FurmanovC, Saifi FC, Meidan RC, Davidson EPI. (2016) The Effect of Medicinal Cannabis on Pain and Quality of Life Outcomes in Chronic Pain: a Prospective Open-Label Study. Clinical Journal of Pain